BACKGROUND Glycolic acid is a C2 hydroxy acid that is a widely used chemical compound. It can be polymerised to produce biodegradable polymers with excellent gas barrier properties. Currently, glycolic acid is produced in a chemical process using fossil resources and toxic chemicals. Biotechnological production of glycolic acid using renewable resources is a desirable alternative. RESULTS The...

BACKGROUND Glycolic acid has been used extensively for the treatment of photoaging and wrinkles. Suggestions have been made that glycolic acid may have specific dermal effects, although biochemical studies are limited. OBJECTIVE This study's purpose was to examine the effect of glycolic acid on the radioactively labeled collagen production in human skin fibroblasts in culture. METHODS Norma...

Background: Comedone formation has an essential role in pathophysiology of acne, therefore destroying of comedones and preventing of comedone formation is very important in acne treatment. Objective: To determine the effect of superficial peeling with 70% glycolic acid in the improvement of acne. Patients and Methods: In this open clinical trial without control group, 30 patients with acn...

Studies with glycolic acid oxidase and glyoxylic acid reductase isolated from green leaves have led to the suggestion that these enzymes play a part in the oxygen uptake of leaf tissue (l-3). Glycolic acid oxidase is a flavoprotein which is capable of directly oxidizing glycolic acid, a substance rapidly produced during photosynthesis (4, 5). As has been demonstrated in model systems, the oxida...

Glycolic acid has been su,ggested as a major substrate for photorespiration. According to Zelitch (5,6), respiration in the light is several times greater than dark respiration because many plants in the Iiloht synthesize large quantities of glycolic acid which is then oxidized, in 'part at least, to CO2. Yet little glycolic acid is ever found in normal illuminated leaves. If any significant am...

Clagett, Tolbert, and Burris (1) discovered an enzyme of wide-spread occurrence in the green parts of many plants which catalyzes the oxidation of glycolic and L-lactic acids. The enzyme, which was partially purified from tobacco leaves, seemed to catalyze the oxidation of glycolic acid, through glyoxylic acid, to formic acid and CO, (2). In view of the possible importance of glycolic acid oxid...

BACKGROUND Glycolic acid has become important and popular for treating acne. OBJECTIVE To evaluate the efficacy and safety of serial glycolic acid peels with glycolic acid home care products on facial acne lesions and other associated skin problems. METHODS We collected 40 Asian candidates with moderate to moderately severe acne. They were divided into two groups according to the degree of ...

Tensile stress and tensile strain directly affect the quality of nerve regeneration after bridging nerve defects by poly(lactic-co-glycolic acid) conduit transplantation and autogenous nerve grafting for sciatic nerve injury. This study collected the sciatic nerve from the gluteus maximus muscle from fresh human cadaver, and established 10-mm-long sciatic nerve injury models by removing the isc...

9. SCHOU, L., BENSON, A. A., BASSHAM, J. A., and CALVIN, M. The path of carbon in photosynthesis. XI. The role of glycolic acid. Physiol. Plantarum 3: 487-495. 1950. 10. THIMANN, K. V. and BONNER, W. D., JR. Organic acid metabolism. Ann. Rev. Plant Physiol. 1: 75-108. 1950. 11. TOLBERT, N. E. and BURRIS, R. H. Light activation of the plant enzyme which oxidizes glycolic acid. Jour. Biol. Chem. ...